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Marriages and Genotype Compatibility – All You Need to Know (Part I)

Health Tips

There has been a lot of focus on this topic in recent times, and it is only natural that we lend a voice to it in order to expand the horizon of the information about what you must know about Genotype and Blood Group compatibility. We did a little reading, surfing the internet, and asked questions to bring forth majority of the information you are about to get.

First things first, being assured of Genotype and Blood Group compatibility with your partner is one of the most important factors of long-term happiness in your marriage, it helps you raise healthy children, and saves you a lot of stress in the happy marriage you dream of with your partner.

Your genotype is your complete heritable genetic identity; it is your unique genome that would be revealed by personal genome sequencing. However, the word genotype can also refer just to a particular gene or set of genes carried by an individual. For example, if you carry a mutation that is linked to diabetes, you may refer to your genotype just with respect to this mutation without consideration of all the other gene variants that your may carry.

This is different from your phenotype which is a description of your actual physical characteristics. This includes straightforward visible characteristics like your height and eye color, but also your overall health, your disease history, and even your behavior and general disposition. Do you gain weight easily? Are you anxious or calm? Do you like cats? These are all ways in which you present yourself to the world, and as such are considered phenotypes. However, not all phenotypes are a direct result of your genotype; chances are that your personal disposition to cats is the result of your life’s experience with pets rather than a mutation in a hypothetical cat fancier gene. This article however focuses on the genotype and blood group compatibility, so we keep it that way.
The genotypes in humans are AA, AS, AC, SS, SC, CC.

Truth be told, I didn’t know there was any genotype like AC and SC until I was researching for this article and found it online.

Now let’s explain what all the AAs and ACs mean.

According to an online publication by Laumsites Ywc – What you have in your blood are cells, the most predominant of which are called RED BLOOD CELLS (RBCs).

These cells contain within them HEMOGLOBIN, a substance without which the RBCs are invariably useless.
This hemoglobin itself is composed of 2 parts: a heme (don’t bother yourself, this basically is a complex Iron-protein complex) and globin (2 pairs of protein chains, this is the important part).

There are 2 alpha and 2 beta globin chains – the pair, and there is a normal way the chains are supposed to be structured.
The error happens when a protein substitution occurs in any one of these chains – but particularly in the globin chains (First of all, you have to understand that amino acids are the building blocks of proteins – so if amino acid ‘x’ is the normal, an abnormality occurs when instead of ‘x’ at a particular location along the chain, you have ‘y’.)
There are different types of Hemoglobin; among them are Hemoglobin A, Hemoglobin S and Hemoglobin C.
Hemoglobin C is very rare.

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